| CAMPEONATO DE CLAUSURA 2021 | ||||
| 1º Fecha | ||||
| 8-ene-2021 | Puebla | Puebla | 1 | Ormeño |
| Guadalajara | 1 | Ponce | ||
| 9-ene-2021 | Tijuana | Tijuana | 0 | |
| Pumas | 0 | |||
| 9-ene-2021 | Mazatlan | Mazatlan | 3 | Aristeguieta, Vargas, Sanvezzo (P) |
| Necaxa | 2 | Delgado, Zendejas | ||
| 9-ene-2021 | Guadalajara | Atlas | 0 | |
| Monterrey | 2 | Funes Mori (2, 1P) | ||
| 9-ene-2021 | San Nicolas | Tigres | 2 | Gignac, Gonzalez |
| de los Garza | Leon | 0 | ||
| 10-ene-2021 | Ciudad | America | 2 | Lainez, Cordova |
| de Mexico | San Luis | 1 | Ibañez | |
| 10-ene-2021 | Toluca | Toluca | 3 | Castañeda, Canelo, Estrada |
| Queretaro | 1 | Sepulveda (P) | ||
| 10-ene-2021 | Torreo | Santos | 1 | Valdes |
| Cruz Azul | 0 | |||
| 12-ene-2021 | Pachuca | Pachuca | 1 | Quiroga |
| Juarez | 1 | Velazquez | ||
| 2º Fecha | ||||
| 15-ene-2021 | Aguascalientes | Necaxa | 1 | Gonzalez (P) |
| San Luis | 0 | |||
| 16-ene-2021 | Ciudad Juarez | Juarez | 0 | |
| Tijuana | 0 | |||
| 16-ene-2021 | Zapopan | Guadalajara | 1 | Molina |
| Toluca | 1 | Castañeda | ||
| 16-ene-2021 | Ciudad | Cruz Azul | 0 | |
| de Mexico | Puebla | 1 | Tabo | |
| 17-ene-2021 | Guadalupe | Monterrey | 1 | Funes Mori (P) |
| America | 0 | |||
| 17-ene-2021 | Ciudad | Pumas | 3 | Waller, Gutierrez, Montejano |
| de Mexico | Mazatlan | 0 | ||
| 17-ene-2021 | Torreon | Santos | 2 | Otero, Aguirre |
| Tigres | 0 | |||
| 18-ene-2021 | Queretaro | Queretaro | 1 | Chico |
| Atlas | 0 | |||
| 19-ene-2021 | Leon | Leon | 0 | |
| Pachuca | 0 | |||
| 3º Fecha | ||||
| 22-ene-2021 | San Luis Potosi | San Luis | 3 | Gonzalez, Ibañez (2, 1P) |
| Guadalajara | 1 | Macias | ||
| 22-ene-2021 | Puebla | Puebla | 0 | |
| Tijuana | 1 | Martinez (P) | ||
| 23-ene-2021 | Mazatlan | Mazatlan | 0 | |
| Santos | 0 | |||
| 23-ene-2021 | Guadalajara | Atlas | 0 | |
| Tigres | 2 | Gonzalez, Quiñones | ||
| 24-ene-2021 | Toluca | Toluca | 2 | Estrada (P), Plata |
| Necaxa | 0 | |||
| 24-ene-2021 | Queretaro | Queretaro | 2 | Gurrola, Sepulveda |
| Pumas | 0 | |||
| 26-ene-2021 | Pachuca | Pachuca | 0 | |
| Cruz Azul | 1 | Escobar | ||
| 26-ene-2021 | Ciudad | America | 2 | Aguilera, Martinez |
| de Mexico | Juarez | 0 | ||
| 11-mar-2021 | Guadalupe | Monterrey | 1 | Funes Mori (P) |
| Leon | 1 | Davila | ||
| 4º Fecha | ||||
| 29-ene-2021 | San Nicolas | Tigres | 1 | Salcedo |
| de los Garza | Necaxa | 1 | Barragan | |
| 30-ene-2021 | Mazatlan | Mazatlan | 1 | Aristeguieta |
| Pachuca | 0 | |||
| 30-ene-2021 | Zapopan | Guadalajara | 1 | Macias |
| Juarez | 2 | Lezcano, Garcia | ||
| 31-ene-2021 | Ciudad | Cruz Azul | 4 | Aldrete, Pineda, Rodriguez, Hernandez |
| de Mexico | Queretaro | 1 | Sepulveda | |
| 31-ene-2021 | Tijuana | Tijuana | 3 | Manotas, Martinez, Sansores |
| Toluca | 2 | Canelo, Barbieri | ||
| 31-ene-2021 | Ciudad | Pumas | 0 | |
| de Mexico | Atlas | 0 | ||
| 31-ene-2021 | Torreon | Santos | 1 | Muñoz |
| America | 1 | Martin | ||
| 31-ene-2021 | Leon | Leon | 3 | Davila (2), Meneses |
| San Luis | 1 | Berterame | ||
| 3-feb-2021 | Puebla | Puebla | 0 | |
| Monterrey | 0 | |||
| 5º Fecha | ||||
| 4-feb-2021 | San Luis Potosi | San Luis | 2 | Castro, Gallegos |
| Tijuana | 2 | Martinez (2, 1P) | ||
| 5-feb-2021 | Queretaro | Queretaro | 3 | Madrigal, Valencia, Ramirez |
| Pachuca | 1 | Magallanes (A) | ||
| 6-feb-2021 | Aguascalientes | Necaxa | 0 | |
| Cruz Azul | 2 | Romo, Escobar | ||
| 6-feb-2021 | Guadalajara | Atlas | 1 | Herrera |
| Santos | 1 | Campos | ||
| 6-feb-2021 | Ciudad | America | 1 | Martinez |
| de Mexico | Puebla | 0 | ||
| 7-feb-2021 | Guadalupe | Monterrey | 1 | Loba |
| Pumas | 0 | |||
| 7-feb-2020 | Toluca | Toluca | 4 | Canelo (3), Sambueza |
| Mazatlan | 1 | Sanvezzo | ||
| 9-feb-2021 | Leon | Leon | 1 | Briseño (A) |
| Guadalajara | 3 | Sanchez, Macias, Mayorga | ||
| 14-abr-2021 | Ciudad Juarez | Juarez | 2 | Mendieta, Velazquez |
| Tigres | 3 | Lopez (2), Reyes | ||
| 6º Fecha | ||||
| 12-feb-2021 | Puebla | Puebla | 4 | Ormeño (3, 1P), Tabo |
| Juarez | 0 | |||
| 13-feb-2021 | Tijuana | Tijuana | 2 | Manotas, Castillo |
| Leon | 0 | |||
| 13-feb-2021 | Mazatlan | Mazatlan | 0 | |
| San Luis | 3 | Ibañez (2, 1P), Berterame | ||
| 13-feb-2021 | Zapopan | Guadalajara | 2 | Angulo, Macias |
| Necaxa | 2 | Gonzalez, Macias (A) | ||
| 14-feb-2021 | Ciudad | America | 2 | Naveda, Martin |
| de Mexico | Queretaro | 1 | Sepulveda | |
| 14-feb-2021 | Toluca | Toluca | 1 | Canelo |
| Pumas | 0 | |||
| 14-feb-2021 | Torreon | Santos | 1 | Doria |
| Monterrey | 0 | |||
| 16-feb-2021 | Pachuca | Pachuca | 0 | |
| Atlas | 1 | Malcorra (P) | ||
| 18-feb-2021 | San Nicolas | Tigres | 0 | |
| de los Garza | Cruz Azul | 2 | Romo, Fernandez | |
| 7º Fecha | ||||
| 19-feb-2021 | San Luis Potosi | San Luis | 1 | Ibañez |
| Santos | 0 | |||
| 19-feb-2021 | Aguascalientes | Necaxa | 1 | Barragan |
| Monterrey | 1 | Meza | ||
| 20-feb-2021 | Ciudad Juarez | Juarez | 1 | Lezcano |
| Mazatlan | 0 | |||
| 20-feb-2021 | Ciudad | Cruz Azul | 3 | Rodriguez, Alvarado, Fernandez |
| de Mexico | Toluca | 2 | Barbieri, Canelo (P) | |
| 21-feb-2021 | Guadalajara | Atlas | 3 | |
| (*) | America | 0 | Martin (P), Sanchez | |
| 21-feb-2021 | Ciudad | Pumas | 0 | |
| de Mexico | Leon | 1 | Mena | |
| 21-feb-2021 | Queretaro | Queretaro | 1 | Gallardo |
| Puebla | 1 | Alvarez (P) | ||
| 21-feb-2021 | San Nicolas | Tigres | 3 | Quiñones, Lopez (2) |
| de los Garza | Tijuana | 2 | Lopez, Barbona | |
| 23-feb-2021 | Pachuca | Pachuca | 1 | Cabral |
| Guadalajara | 1 | Molina | ||
| (*) Atlas gana el partido por mala inscripcion de un jugador de America. | ||||
| 8º Fecha | ||||
| 26-feb-2021 | San Luis Potosi | San Luis | 2 | Castro, Ibañez |
| Tigres | 2 | Lopez (2) | ||
| 26-feb-2021 | Puebla | Puebla | 1 | Gularte |
| Necaxa | 0 | |||
| 27-feb-2021 | Mazatlan | Mazatlan | 3 | Aristeguieta, Sanvezzo, Diaz |
| Queretaro | 0 | |||
| 27-feb-2021 | Toluca | Toluca | 0 | |
| Atlas | 0 | |||
| 27-feb-2021 | Ciudad | America | 2 | Sanchez, Aquino |
| de Mexico | Pachuca | 0 | ||
| 28-feb-2021 | Leon | Leon | 0 | |
| Cruz Azul | 1 | Angulo | ||
| 28-feb-2021 | Guadalupe | Monterrey | 1 | Meza |
| Tijuana | 1 | Manotas | ||
| 28-feb-2021 | Torreon | Santos | 3 | Garcia (A), Muñoz, Doria |
| Juarez | 2 | Pavez, Lezcano (P) | ||
| 1-mar-2021 | Zapopan | Guadalajara | 2 | Macias, Mayorga |
| Pumas | 1 | Torres | ||
| 9º Fecha | ||||
| 2-mar-2021 | Guadalajara | Atlas | 3 | Rocha, Torres, Marquez |
| San Luis | 1 | Berterame | ||
| 2-mar-2021 | San Nicolas | Tigres | 0 | |
| de los Garza | Toluca | 1 | Canelo | |
| 3-mar-2021 | Leon | Leon | 1 | Mena (P) |
| Puebla | 2 | Ormeño (P), Alvarez | ||
| 3-mar-2021 | Queretaro | Queretaro | 2 | Silveira, Ramirez |
| Guadalajara | 2 | Macias, Ponce | ||
| 3-mar-2021 | Ciudad Juarez | Juarez | 1 | Lezcano |
| Monterrey | 6 | Janssen (2), Gonzalez, Funes Mori (2), Alvarado | ||
| 4-mar-2021 | Ciudad | Cruz Azul | 1 | Alvarado |
| de Mexico | Mazatlan | 0 | ||
| 4-feb-2021 | Tijuana | Tijuana | 0 | |
| America | 2 | Aquino, Martin | ||
| 4-mar-2021 | Aguascalientes | Necaxa | 2 | Zendejas, Salas |
| Pachuca | 2 | Nurse, Quiroga | ||
| 5-mar-2021 | Ciudad | Pumas | 1 | Dinenno (P) |
| de Mexico | Santos | 0 | ||
| 10º Fecha | ||||
| 5-mar-2021 | San Luis Potosi | San Luis | 0 | |
| Toluca | 0 | |||
| 6-mar-2021 | Puebla | Puebla | 1 | Ormeño |
| Tigres | 1 | Gignac (P) | ||
| 6-mar-2021 | Guadalajara | Atlas | 2 | Torres, Ibarra |
| Juarez | 0 | |||
| 6-mar-2021 | Ciudad | America | 2 | Martin, Viñas |
| de Mexico | Leon | 1 | Davila | |
| 6-mar-2021 | Guadalupe | Monterrey | 2 | Funes Mori (2, 1P) |
| Queretaro | 1 | Sepulveda | ||
| 7-mar-2021 | Mazatlan | Mazatlan | 1 | Diaz |
| Guadalajara | 1 | Molina | ||
| 7-mar-2021 | Torreon | Santos | 3 | Muñoz, Otero, Gorriaran |
| Necaxa | 1 | Lopez | ||
| 8-mar-2021 | Ciudad | Pumas | 0 | |
| de Mexico | Cruz Azul | 1 | Rodriguez (P) | |
| 9-mar-2021 | Pachuca | Pachuca | 2 | Sosa (P), Alvarez |
| Tijuana | 1 | Castillo | ||
| 11º Fecha | ||||
| 12-mar-2021 | Puebla | Puebla | 0 | |
| Atlas | 1 | Rocha | ||
| 13-mar-2021 | Ciudad Juarez | Juarez | 1 | Garcia |
| Pumas | 1 | Dinenno | ||
| 13-mar-2021 | San Nicolas | Tigres | 1 | Gonzalez |
| de los Garza | Mazatlan | 2 | Rangel, Giovanni Augusto | |
| 14-mar-2021 | Ciudad | Cruz Azul | 1 | Alvarado |
| de Mexico | Monterrey | 0 | ||
| 14-mar-2021 | Tijuana | Tijuana | 0 | |
| Santos | 1 | Torres | ||
| 14-mar-2021 | Toluca | Toluca | 0 | |
| Pachuca | 2 | De la Rosa, Chavez (P) | ||
| 14-mar-2021 | Queretaro | Queretaro | 2 | Sepulveda (P), Silveira |
| San Luis | 1 | Ibañez (P) | ||
| 14-mar-2021 | Zapopan | Guadalajara | 0 | |
| America | 3 | Martin (2), Cordova | ||
| 16-mar-2021 | Leon | Leon | 3 | Campbell, Colombatto, Mena |
| Necaxa | 1 | Salas | ||
| 12º Fecha | ||||
| 18-mar-2021 | Pachuca | Pachuca | 1 | De la Rosa |
| Tigres | 0 | |||
| 19-mar-2021 | Aguascalientes | Necaxa | 1 | Gonzalez |
| Juarez | 0 | |||
| 20-mar-2021 | Mazatlan | Mazatlan | 0 | |
| America | 1 | Ortiz (A) | ||
| 20-mar-2021 | San Luis Potosi | San Luis | 0 | |
| Pumas | 1 | Dinenno (P) | ||
| 20-mar-2021 | Ciudad | Cruz Azul | 3 | Angulo, Rodriguez (2) |
| de Mexico | Atlas | 2 | Santamaria, Caraglio (P) | |
| 21-mar-2021 | Tijuana | Tijuana | 3 | Martinez (2), Manotas |
| Queretaro | 1 | Guzman (A) | ||
| 21-mar-2021 | Toluca | Toluca | 4 | Estrada (2), Canelo (P), Diego |
| Puebla | 4 | Ormeño (P), Segovia, Aguilar, Alvarez | ||
| 21-mar-2021 | Torreon | Santos | 1 | Gorriaran (P) |
| Leon | 2 | Mena (P), Navarro | ||
| 21-abr-2021 | Guadalupe | Monterrey | 1 | Janssen |
| Guadalajara | 2 | Brizuela, Vega | ||
| 13º Fecha | ||||
| 2-abr-2021 | Puebla | Puebla | 3 | Ormeño (P), Reyes, Araujo |
| Mazatlan | 1 | Giovanni Augusto | ||
| 3-abr-2021 | Ciudad Juarez | Juarez | 0 | |
| Cruz Azul | 1 | Rodriguez | ||
| 3-abr-2021 | Guadalajara | Atlas | 1 | Ibarra |
| Tijuana | 0 | |||
| 3-abr-2021 | Ciudad | America | 2 | Sanchez, Dos Santos |
| de Mexico | Necaxa | 1 | Barragan | |
| 4-abr-2021 | Guadalupe | Monterrey | 2 | Meza, Funes Mori |
| San Luis | 0 | |||
| 4-abr-2021 | Ciudad | Pumas | 2 | Saucedo, Dinenno (P) |
| de Mexico | Pachuca | 2 | Sosa, Sanchez | |
| 4-abr-2021 | Zapopan | Guadalajara | 1 | Angulo |
| Santos | 1 | Ocejo | ||
| 4-abr-2021 | Queretaro | Queretaro | 0 | |
| Tigres | 1 | Reyes | ||
| 4-abr-2021 | Leon | Leon | 2 | Barreiro, Mena |
| Toluca | 1 | Estrada | ||
| 14º Fecha | ||||
| 9-abr-2021 | Aguascalientes | Necaxa | 0 | |
| Pumas | 1 | Vigon | ||
| 9-abr-2021 | Ciudad Juarez | Juarez | 2 | Lezcano (P), Contreras |
| San Luis | 1 | Ibañez (P) | ||
| 10-abr-2021 | Guadalajara | Atlas | 1 | Zaldivar |
| Leon | 3 | Gigliotti (2), Rodriguez | ||
| 10-abr-2021 | Ciudad | Cruz Azul | 1 | Rodriguez |
| de Mexico | Guadalajara | 0 | ||
| 10-abr-2021 | San Nicolas | Tigres | 1 | Reyes |
| de los Garza | America | 3 | Martinez (2), Aquino | |
| 11-abr-2021 | Toluca | Toluca | 1 | Torres |
| Monterrey | 2 | Vegas, Meza | ||
| 11-abr-2021 | Queretaro | Queretaro | 1 | Montes |
| Santos | 0 | |||
| 11-abr-2021 | Tijuana | Tijuana | 2 | Manotas, Martinez (P) |
| Mazatlan | 3 | Sanvezzo (2P), Rangel | ||
| 12-abr-2021 | Pachuca | Pachuca | 1 | Sanchez |
| Puebla | 3 | Araujo, Perg, Reyes | ||
| 15º Fecha | ||||
| 16-abr-2021 | Aguascalientes | Necaxa | 0 | |
| Queretaro | 0 | |||
| 16-abr-2021 | Mazatlan | Mazatlan | 0 | |
| Atlas | 0 | |||
| 17-abr-2021 | San Luis Potosi | San Luis | 1 | Gallegos |
| Puebla | 4 | Ormeño, Tabo, Alvarez (P), Martinez | ||
| 17-abr-2021 | Zapopan | Guadalajara | 2 | Vega, Angulo |
| Tijuana | 0 | |||
| 17-abr-2021 | Ciudad | America | 1 | Aguilera |
| de Mexico | Cruz Azul | 1 | Rodriguez (P) | |
| 18-abr-2021 | Ciudad | Pumas | 0 | |
| de Mexico | Tigres | 0 | ||
| 18-abr-2021 | Torreon | Santos | 3 | Aguirre (2), Otero |
| Toluca | 1 | Canelo | ||
| 18-abr-2021 | Guadalupe | Monterrey | 0 | |
| Pachuca | 1 | Aguirre | ||
| 19-abr-2021 | Leon | Leon | 2 | Meneses, Davila |
| Juarez | 0 | |||
| 16º Fecha | ||||
| 23-abr-2021 | Puebla | Puebla | 0 | |
| Pumas | 0 | |||
| 23-abr-2021 | Tijuana | Tijuana | 1 | Martinez |
| Necaxa | 0 | |||
| 23-abr-2021 | Mazatlan | Mazatlan | 4 | Rangel (2), Giovanni Augusto, Mosquera (A) |
| Leon | 3 | Montes, Davila, Mena | ||
| 24-abr-2021 | Ciudad | Cruz Azul | 3 | Hernandez, Rodriguez (P), Aguilar |
| de Mexico | San Luis | 2 | Ibañez (P), Dominguez (A) | |
| 24-abr-2021 | Guadalajara | Atlas | 0 | |
| Guadalajara | 1 | Zaldivar | ||
| 24-abr-2021 | San Nicolas | Tigres | 2 | C. Gonzalez, Gignac (P) |
| de los Garza | Monterrey | 1 | A. Gonzalez | |
| 25-abr-2021 | Toluca | Toluca | 3 | Estrada, Lopez, Canelo |
| America | 1 | Aguilera (P) | ||
| 25-abr-2021 | Queretaro | Queretaro | 1 | Silveira |
| Juarez | 0 | |||
| 26-abr-2021 | Pachuca | Pachuca | 1 | Sosa (P) |
| Santos | 0 | |||
| 17º Fecha | ||||
| 29-abr-2021 | San Luis Potosi | San Luis | 1 | Gonzalez |
| Pachuca | 5 | De la Rosa (2), Sanchez (2), Ibarra | ||
| 30-abr-2021 | Aguascalientes | Necaxa | 1 | Delgado |
| Atlas | 5 | Herrera (2), Torres, Rocha (P), Furch | ||
| 30-abr-2021 | Ciudad Juarez | Juarez | 1 | Galvan |
| Toluca | 0 | |||
| 1-may-2021 | Zapopan | Guadalajara | 0 | |
| Tigres | 0 | |||
| 1-may-2021 | Leon | Leon | 2 | Mena (2P) |
| Queretaro | 1 | Doldan | ||
| 1-may-2021 | Ciudad | Cruz Azul | 1 | Pineda |
| de Mexico | Tijueana | 1 | Lopez | |
| 1-may-2021 | Guadalupe | Monterrey | 1 | Janssen |
| Mazatlan | 0 | |||
| 2-may-2021 | Torreon | Santos | 0 | |
| Puebla | 0 | |||
| 2-may-2021 | Ciudad | Pumas | 0 | |
| de Mexico | America | 1 | Martin | |
| Playoffs | ||||
| 8-may-2021 | Guadalajara | Atlas | 1 | Furch |
| Tigres | 0 | |||
| 8-may-2021 | Torreon | Santos | 5 | Gorriaran, Preciado, Aguirre (2), Valdes (P) |
| Queretaro | 0 | |||
| 9-may-2021 | Leon | Leon | 2(2) | Davila, Ambriz |
| Toluca | 2(4) | Castañeda, Canelo | ||
| 9-may-2021 | Pachuca | Pachuca | 4 | Murillo (2), De la Rosa (2) |
| Guadalajara | 2 | Antuna (2, 1P) | ||
| Cuartos de Final | ||||
| 12-may-2021 | Toluca | Toluca | 2 | Canelo (P), Estrada (P) |
| Cruz Azul | 1 | Fernandez | ||
| 15-may-2021 | Ciudad | Cruz Azul | 3 | Angulo, Rodriguez (P), Gimenez |
| de Mexico | Toluca | 1 | Canelo | |
| 12-may-2021 | Guadalajara | Atlas | 1 | Torres |
| Puebla | 0 | |||
| 15-may-2021 | Puebla | Puebla | 1 | Santamaria (A) |
| Atlas | 0 | |||
| 13-may-2021 | Pachuca | Pachuca | 3 | Aguirre, Pardo, Chavez |
| America | 1 | Suarez | ||
| 16-may-2021 | Ciudad | America | 4 | Martinez (2, 1P), Fuentes, Suarez |
| de Mexico | Pachuca | 2 | Ibarra, Cabral (P) | |
| 13-may-2021 | Torreon | Santos | 2 | Aguirre, Preciado |
| Monterrey | 1 | Janssen | ||
| 16-may-2021 | Guadalupe | Monterrey | 1 | Meza |
| Santos | 1 | Prieto | ||
| Semifinales | ||||
| 19-may-2021 | Pachuca | Pachuca | 0 | |
| Cruz Azul | 0 | |||
| 22-may-2021 | Ciudad | Cruz Azul | 1 | Gimenez |
| de Mexico | Pachuca | 0 | ||
| 20-may-2021 | Torreon | Santos | 3 | Aguirre (2), Preciado |
| Puebla | 0 | |||
| 23-may-2021 | Puebla | Puebla | 1 | Ormeño |
| Santos | 0 | |||
| FINAL | ||||
| 27-may-2021 | Torreon | Santos | 0 | |
| Cruz Azul | 1 | Romo | ||
| 30-may-2021 | Ciudad | Cruz Azul | 1 | Rodriguez |
| de Mexico | Santos | 1 | Valdes | |